
WHO Revises Global Health Threats List for 2025
The World Health Organization has released its updated list of global health threats, adding antimicrobial resistance and airborne virus transmission as critical priorities for international health security. This comprehensive assessment reflects the evolving landscape of infectious diseases and emerging health challenges worldwide.
New Additions to Priority Threats
Antimicrobial resistance (AMR) has been elevated to the highest level of concern, with WHO officials describing it as "one of the top global public health threats facing humanity." The organization estimates that bacterial AMR was directly responsible for 1.27 million global deaths in recent years and contributed to nearly 5 million additional deaths. Without urgent action, AMR could cause up to 10 million annual deaths by 2050.
Airborne transmission of viruses has also been added as a distinct category, reflecting lessons learned from the COVID-19 pandemic. This includes pathogens that spread through aerosols and droplets, capable of traveling significant distances and remaining infectious in indoor environments for extended periods.
Existing Priority Diseases
The updated list maintains several known threats including:
- COVID-19 and other coronaviruses
- Ebola virus disease
- Marburg virus disease
- Lassa fever
- Crimean-Congo hemorrhagic fever
- Nipah and henipaviral diseases
- Rift Valley fever
- Zika virus
- Disease X (representing unknown pathogens)
Why These Updates Matter
Dr. Maria Van Kerkhove, WHO's technical lead for COVID-19 response, emphasized that "the inclusion of antimicrobial resistance and airborne transmission reflects our growing understanding of how pathogens spread and evolve. These are not theoretical threats—they are happening now and require coordinated global action."
The updated list serves as a guide for research and development priorities, helping governments and pharmaceutical companies focus resources on the most pressing health challenges. It also informs international health regulations and preparedness planning.
Global Response and Preparedness
WHO is calling for increased investment in surveillance systems, diagnostic tools, and treatment options for these threats. The organization emphasizes the need for better antimicrobial stewardship programs to combat resistance and improved ventilation standards in public spaces to reduce airborne transmission.
Countries are encouraged to develop national action plans addressing these specific threats, with particular focus on strengthening healthcare systems and promoting international collaboration in research and response efforts.